Most denture cream is slowly dissolved by your saliva, and studies have shown that it generally passes through your body without any ill side effects. Denture adhesive creams and similar compositions provide the desirable mechanical and aesthetic properties, at a minimum of cost, making these types of products inexpensive and effective for securing the dentures in your mouth. Being water soluble, these fixatives can dissolve, wash out, and result in the dentures slipping and sliding. Most denture creams are water-soluble and can be washed out by eating or drinking which may not be desirable at times.

Zinc is a very common ingredient in many over the counter and FDA approved products. Zinc is an essential mineral that is found in almost every cell in the body and in foods like red meat, poultry, whole grains and beans and is necessary for the maintenance of good health and nutrition. The potential for absorption of zinc through the gums is minimal but does happen. Zinc denture cream may adversely impact your health and create a copper deficiency in your body if left unchecked. If your mouth absorbs an excess of zinc, this overdose can lead to hypocupremia and neurologic diseases. Many studies have been performed on zinc over dose and neurological disease. All the studies of denture cream zinc overdose reached the following conclusion: Denture cream containing zinc and chronic excessive use may result in hyopcupremia. Tests for zinc levels in your blood can determine quickly whether you have a zinc overdose in your body. Action should be taken immediately against zinc pPoisoning if you or someone you care about has been experiencing symptoms such as numbness, tingling along nerve pathways and hypersensitivity and you use Poligrip or Fixodent, please consider being examined by your doctor. People who incur permanent damage from zinc poisoning due to use of denture creams may be eligible for compensation for loss, suffering and medical treatments.